ABSTRACT Frequent recombination is a hallmark of retrovirus replication.In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health.These recombinants may initially have substantial replication defects due to impaired interactions between protei
Amy Guo,1 Michael Grabner,2 Swetha Rao Palli,2 Jessica Elder,1 Matthew Sidovar,1 Peter Aupperle,1 Stephen Krieger3 1Acorda Therapeutics Inc., Ardsley, New York, NY, USA; 2HealthCore Inc., Wilmington, DE, USA; 3Corinne Goldsmith Dickinson Center for MS, Icahn School of Medicine at Mount Sinai, New York, NY, USA Background: Although previous stu
Implantation of a biomaterial is one of the important trends in solving the problem of bone tissue loss.Calcium hydroxiapatite (HAp), as the most representative bone component is a serious candidate for such implantations.The synthetic polymer poly-L-lactide (PLLA) in HAp/PLLA is often used as a polymeric material, with a role in the substitution o
Urban flooding nowadays becomes common throughout the world.The main reason for these floods is rapid urban development and climate change.During the monsoon, the flows in the urban drains will be high and the main reason for these high flows is the existence of a combined network system (i.e.drainage and stormwater).Further, the flow in the city (
Even if the polarizing discussion about instructive and constructive teaching approaches is widely overcome, some misapprehensions still quadruple topical ointment for dogs seem to distort the discourse.Thereby thesis, like the future of teaching would only lie in self-directed, process-oriented, casuistic and interdisciplinary learning (predominan